Posted on September 10th, 2009 by Kelley Luckstein
Researchers from Mayo Clinic Florida in Jacksonville and Harvard Medical School have found that a protein thought to protect against cancer development can actually spur the spread of tumors.
FOXO3a, a transcription factor that regulates gene expression, becomes active when growing cancer cells begin to starve…“This is a complete reversal of what everyone thought about FOXO3a — that we should find a way to activate this transcription factor so as to fight cancer growth,” said cancer biologist Dr. Peter Storz, the study’s lead investigator at Mayo Clinic Florida.
Triangle Business Journal, 09/04/09
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