With the help of mice, researchers have now found that mitochondria in the brain are dysfunctional early on in Alzheimer's disease, even before memory loss. The team examined mitochondria in three mouse models, each using a different gene shown to cause familial, or early-onset, Alzheimer's disease…"One of the most significant findings of this study is our discovery of the impact of mitochondrial dysfunction in Alzheimer's disease," Eugenia Trushina, Ph.D., Mayo Clinic pharmacologist and senior investigator on the study, was quoted saying.

Ivanhoe     3/5/12

Tags: alzheimer's disease, Dr. Eugenia Trushina, Pharmacology, Research