March 24th, 2017
Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note to Emily Blahnik with this subject line: SUBSCRIBE to Mayo Clinic in the News.
New York Times
The Best Exercise for Aging Muscles
by Gretchen Reynolds
Exercise is good for people, as everyone knows. But scientists have surprisingly little understanding of its cellular impacts and how those might vary by activity and the age of the exerciser. So researchers at the Mayo Clinic in Rochester, Minn., recently conducted an experiment on the cells of 72 healthy but sedentary men and women who were 30 or younger or older than 64. After baseline measures were established for their aerobic fitness, their blood-sugar levels and the gene activity and mitochondrial health in their muscle cells, the volunteers were randomly assigned to a particular exercise regimen. It seems as if the decline in the cellular health of muscles associated with aging was “corrected” with exercise, especially if it was intense, says Dr. Sreekumaran Nair, a professor of medicine and an endocrinologist at the Mayo Clinic and the study’s senior author.
Reach: The New York Times has a daily circulation of nearly 649,000 and a Sunday circulation of 1.18 million.
Context: Everyone knows that exercise is good for you, but what type of training helps most, especially when you’re older - say over 65? A Mayo Clinic study says it’s high-intensity aerobic exercise, which can reverse some cellular aspects of aging. The findings appear in Cell Metabolism. Mayo researchers compared high-intensity interval training, resistance training and combined training. All training types improved lean body mass and insulin sensitivity, but only high-intensity and combined training improved aerobic capacity and mitochondrial function for skeletal muscle. Decline in mitochondrial content and function are common in older adults. More information can be found on Mayo Clinic News Network.
Contact: Bob Nellis
Wall Street Journal
Medical School Seeks to Make Training More Compassionate
by Lucette Lagnado
“We found at admission that the kids look fine,” says Liselotte Dyrbye, professor of medicine at Mayo Clinic in Rochester, Minn. “It is as if they go through our training process, and they develop worsening mental health.” Dr. Dyrbye blames this on an “absurd” medical system: “It is the curriculum, it is the learning environment, it is the type of stuff you do as a [young] physician, and it is not unique to Mayo, it is not unique to Sinai.” The Mayo researcher, who studies physician well-being, says in addition to mastering vast amounts of information, medical students and residents cope with “complex patient interactions, the suffering, the deaths.” Too often, “it is not a supportive environment—students are set up to compete with each other.”
Context: Liselotte "Lotte" Dyrbe, M.D., MHPE, is a Mayo Clinic Primary Care Internal Medicine physician. Dr. Dyrbe focuses on the well-being of medical students, residents and physicians. Dr. Dyrbye partners with Tait D. Shanafelt, M.D., and Colin P. West, M.D., Ph.D., to direct the Mayo Clinic Department of Medicine Physician Well-Being Program.
Contact: Matt Brenden
Why your doctor should measure blood pressure in both arms
by A. Pawlowski
Healthy people can have slightly different numbers between arms, but a substantial difference in the readings could signal a blockage or an abnormality, said Dr. Sharonne Hayes, director of the Women's Heart Clinic at the Mayo Clinic in Rochester, Minnesota. “Probably the biggest thing I see in day-to-day practice is somebody who always gets their blood pressure checked in a given arm and they’re told over and over again it’s great,” Hayes told TODAY. But when her office checks the other arm, it reveals uncontrolled high blood pressure that has gone undetected, which can potentially damage the brain and kidneys.
Reach: Today.com is online site for NBC's Today Show.
Context: Sharonne Hayes, M.D. is a Mayo Clinic cardiologist. Dr. Hayes studies cardiovascular disease and prevention, with a focus on sex and gender differences and conditions that uniquely or predominantly affect women. With a clinical base in the Women's Heart Clinic, Dr. Hayes and her research team utilize novel recruitment methods, social media and online communities, DNA profiling, and sex-specific evaluations to better understand several cardiovascular conditions. A major area of focus is spontaneous coronary artery dissection (SCAD), an uncommon and under-recognized cause of acute coronary syndrome (heart attack) that occurs predominantly in young women.
Contact: Traci Klein
Study Connects Genes to Late Onset Alzheimer’s in African-Americans
by Andrea King Collier
A study from researchers at the Mayo Clinic, published in the February issue of the Journal of Alzheimer's Disease, may show some insights into the genetics of the disease in Black Americans who develop the disease after age 65. The study's senior investigator, Dr. Nilufer Ertekin-Taner, M.D., Ph.D., a neurogeneticist and neurologist at Mayo Clinic's Florida campus says that while the reasons for these high rates of Alzheimer's in the Black community remains unknown, there could be multiple reasons. She cites "higher vascular risk factors such as hypertension, diabetes, high cholesterol, as well as differences in genetics and/or differences in socioeconomic factors."
Reach: NBC News provides information about breaking news in business, health, entertainment, politics etc… and receives more than 21,547,025 unique visitors each month.
Context: A Mayo Clinic research team has found a new gene mutation that may be a risk factor for late-onset Alzheimer’s disease in African-Americans. This is the first time this gene has been implicated in the development of this disease in this population. Alzheimer’s disease has been understudied in African-Americans, despite the fact that the disease is twice as prevalent in African-Americans, compared to Caucasians and other ethnic groups. This likely pathogenic variant may be unique to the African-American population, the researchers say. It has not been found in Caucasians with Alzheimer’s disease or in gene repositories from more than 60,000 subjects who are not African-Americans. More information on the study can be found on Mayo Clinic News Network.
Contact: Kevin Punsky
March 19th, 2016
Mayo Clinic in the News is a weekly highlights summary of major media coverage. If you would like to be added to the weekly distribution list, send a note to Emily Blahnik with this subject line: SUBSCRIBE to Mayo Clinic in the News. Thank you.
Latest studies: Brain disease from contact sports more common
by Steve Fainaru and Mark Fainaru-Wada
Latest studies: Brain disease from contact sports more common. Armed with the new definition, researchers at the Mayo Clinic searched for signs of CTE among the 7,000 brains that are preserved at the clinic's Jacksonville, Florida, location. Kevin Bieniek, a postdoctoral research fellow in the Mayo Clinic's Department of Neuroscience, initially narrowed the number to a more manageable 1,800 in an effort to limit his sample to people who participated in contact sports. Bieniek then spent months combing through medical records, obituaries and other resources.
Reach: ESPN Outside the Lines is a sports program that focuses on the most significant sports news of the day. The program airs at 1 pm ET each week day and at 9 am ET on Sundays. ESPN averaged 2.1 million viewers in 2015.
Context: Scientists have recently found evidence that professional football players are susceptible to a progressive degenerative disease, chronic traumatic encephalopathy (CTE), which is caused by repetitive brain trauma. Now, researchers on Mayo Clinic’s Florida campus have discovered a significant and surprising amount of CTE in males who had participated in amateur contact sports in their youth. About one-third of these men whose brains had been donated to the Mayo Clinic Brain Bank had evidence of CTE pathology. CTE only can be diagnosed posthumously.More information on the study can be found on Mayo Clinic News Network.
Contact: Kevin Punsky
US News & World Report
Asians and Obesity: Looks Can Be Deceiving
by Anna Medaris Miller
While only 11 percent of Asian-Americans are obese, they develop obesity-related complications – namely, hypertension and diabetes – at lower BMIs than do people of other backgrounds,
research shows… "The educated [Asian] population knows that they're getting diabetes and hypertension and all these things at a much lower BMI, but if you're in a culture where everybody's really fat and you're thin, you tend to go around and think, 'Well, I'm protected,'" says Dr. Michael Jensen, an endocrinologist at the Mayo Clinic in Rochester, Minnesota, who studies how body fat, and its distribution, influences health. "But [you] may not be.
Context: Michael Jensen, M.D. is a Mayo Clinic endocrinologist. Dr. Jensen and his lab study the effects of obesity and how body fat (adipose tissue) and body fat distribution influence health. The regulated uptake, storage and release of fatty acids from adipose tissue play a major role in determining its health effects.
Contact: Bob Nellis
US News & World Report
What to Eat, Drink and Do to Relieve Constipation
by Michael O. Schroeder
“Exercises help the intestines squeeze and relax and act more normally,” says Dr. Amy Foxx-Orenstein, a gastroenterologist at Mayo Clinic in Scottsdale, Arizona. For those with limited mobility, she adds, Pilates done lying on the floor or tai chi can also assist in stimulating blood flow and intestinal activity, which may help get things going.
Additional coverage: Yahoo! Finance Canada
Contact: Jim McVeigh
The Boston Globe
A new antidote to aging
by Kevin Hartnett
In a sense, your body is a junkyard, slowly filling up with defective cells that clutter your vital organs. The accumulation of these cells—known as senescent cells—has long been thought to be an important reason why people deteriorate physically as they age. “The removal of cells had the same effect as not accumulating senescent cells to begin with,” says Jan van Deursen, a researcher at the Mayo Clinic and coauthor of the paper. “It had profound beneficial effects.”
Reach: The Boston Globe has a daily circulation of more than 274,000 and Sunday circulation of more than 362,000.
Context: Researchers at Mayo Clinic have shown that senescent cells – cells that no longer divide and accumulate with age – negatively impact health and shorten lifespan by as much as 35 percent in normal mice. The results, which appear today in Nature, demonstrate that clearance of senescent cells delays tumor formation, preserves tissue and organ function, and extends lifespan without observed adverse effects. “Cellular senescence is a biological mechanism that functions as an ‘emergency brake’ used by damaged cells to stop dividing,” says Jan van Deursen, Ph.D., Chair of Biochemistry and Molecular biology at Mayo Clinic, and senior author of the paper. “While halting cell division of these cells is important for cancer prevention, it has been theorized that once the ‘emergency brake’ has been pulled, these cells are no longer necessary.” More information can be found on Mayo Clinic News Network.
Mayo Clinic, Boston Scientific team up to develop devices
By Joe Carlson
Passing a wire through a diseased heart valve is a bit like threading a wet noodle into a garden hose while the tap water is flowing. Passing a wire across a heavily calcified heart valve is the first step in many modern procedures to repair or replace it. But threading it through the jet of blood streaming out of the patient's narrowed valve can be a major technical challenge, especially since knocking bits of built-up calcium can trigger serious health problems. Doctors at Mayo Clinic recently had an idea: What if they could aim the wire at the valve using a special catheter with a small funnel on the end to capture the blood flow and center the gadget right above the jet? That idea will be put to use in a human clinical trial later this year as part of a collaboration between Mayo and Boston Scientific Corp. — a long-running collaboration being publicly unveiled Wednesday morning.
Reach: The Star Tribune Sunday circulation is 518,745 copies and weekday circulation is 300,277. The Star Tribune is the state’s largest newspaper and ranks 16th nationally in circulation.
Boston Business Journal — Boston Scientific to speed up research thanks to suspension of device tax
Context: Boston Scientific Corporation (NYSE: BSX) and Mayo Clinic announced this week a continuing collaboration where the two organizations share intellectual property and stimulate the rapid development of medical devices to address unmet clinical needs. More information can be found on Mayo Clinic News Network.
Contact: Duska Anastasijevic
Mayo Clinic to open a nanotechnology lab on Jacksonville, FL campus; will enhance cancer research efforts by Frannie Smith
Mayo Clinic is expanding its cancer research efforts with the opening of a nanotechnology lab at the Florida campus. Mayo Clinic's location in Jacksonville, Florida has been given a $2 million grant from the state to open up the lab. The lab is a key part of Mayo's nanomedicine program.
Reach: KTTC is an NBC affiliate that serves the Rochester, Minn. area including the towns of Austin, Mason City, Albert Lea and Winona. Its website receives more than 73,300 unique visitors each month.
Context: With support from the state of Florida, Mayo Clinic’s Florida campus has opened a state-of-the-art laboratory for nanotechnology research, an emerging field of science that studies and applies materials that are the size of an atom. The laboratory is a key part of Mayo Clinic’s new Translational Nanomedicine Program. The goal is to develop, test and apply tiny materials in diagnosing and treating patients, particularly those with cancer. More information can be found on Mayo Clinic News Network.
Contact: Kevin Punsky