September 25, 2009

FDA Panel Recommends Approval of New Oxycodone Formulation

By Kelley Luckstein

An FDA advisory panel voted to recommend approval of a new formulation of oxycodone hydrochloridepills-out-of-bottle (OxyContin) that is more difficult to crush or dissolve, and which may deter drug abuse.


Although there is no proof that the new formulation is safer, the panel agreed that making the pills harder to crush, chew, or dissolve into liquid may deter abusers. When the new version of the drug is dissolved into water, it produces a gel, which makes snorting the drug more difficult.


"Clearly the old [formulation] is worse than the new, although I think the difference is relatively small," said panelist Randall Flick, MD, an anesthesiologist at the Mayo Clinic who voted to recommend approval of the drug.


MedPage Today by Emily Walker, 09/24/09

Tags: Anesthesiology, Anesthesiology, Oxycodone

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