February 25, 2010

Some Cardiac Surgery Patients May Do Better With Female Donor Plasma for Transfusions

By Kelley Luckstein

Cardiac surgery patients may do better if they receive plasma for transfusions from female donors rather than from male donors, according to a new study published online February 11 in the Journal of Thoracic and Cardiovascular Surgery.


In 2006, the AABB (formerly the American Association of Blood Banks) recommended that plasma for transfusions should come predominantly from male donors to reduce the incidence of transfusion-related acute lung injury (TRALI)…


Another TRALI expert, Ognjen Gajic, MD, associate professor at the Mayo Clinic College of Medicine in Rochester, Minnesota, says the AABB recommendations were based on previous prospective studies and a randomized controlled study, as well as increasing reports of transfusion-related deaths attributed to the plasma and platelets from "potentially alloimunized donors" (ie, women with multiple pregnancies).


Medscape, by Kathryn Foxhall, 2/19/2010

Tags: Ognjen Gajic, plasma tranfusions, Research, transfusion-related acute lung injury (TRALI)…

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