September 30, 2011

Study Finds Noncardiac Sources of Positive Troponin T Tests


Cardiac troponin T (cTnT) is not always cardiac specific and in some cases may lead to a false-positive diagnosis of cardiac injury, according to a study in the Journal of the American College of Cardiology. The study was prompted by a case seen by a senior clinician at the Mayo Clinic in which a patient, who was ultimately found to have a form of muscular dystrophy and no heart disease, had persistent cTnT elevations despite a slew of other negative tests, including negative cardiac troponin I (cTnI). Allan Jaffe and colleagues then sought to find similar myopathy patients treated at the Mayo Clinic’s Neuromuscular Clinic by measuring both cTnT and cTnI.

Forbes, Larry Husten, 9/30/11

Tags: Cardiology

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