May 8, 2012

Study Confirms Genetic Predictor for Fuchs’ Corneal Dystrophy


Mayo Clinic and University of Oregon researchers have confirmed that a genetic factor called a repeating trinucleotide is a strong predictor of an individual's risk of developing the eye condition Fuchs' dystrophy. Fuchs' dystrophy is an eye condition that occurs when the cells at the back of the cornea deteriorate, causing fluid buildup resulting in swelling and cloudy vision. Fuchs' can be inherited. Until recently, the cause for most cases was unknown, but Mayo researchers showed a variation in the gene for transcription factor 4 (TCF4) was a major cause of Fuchs'.

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Tags: Fuchs' dystrophy, Genomics, Medical Xpress, Research, University of Oregon

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