June 28, 2012

Vaccine Shows Promise for Nicotine Addiction


A one-dose vaccine aimed at preventing nicotine addiction showed promise in studies on mice, researchers said Wednesday. In the study, published in the journal Science Translational Medicine, researchers inserted a gene for a nicotine antibody into the liver cells of mice, preventing most of the nicotine given to the animals from reaching the brain, where it could lead to addiction…Those efforts failed in part because the vaccines didn't yield a high enough concentration of antibodies to block the nicotine, said Richard Hurt, an internist and director of the Mayo Clinic's Nicotine Dependence Center in Rochester Minn., who is familiar with those attempts.


Wall Street Journal by Ron Winslow

Tags: Dr. Richard Hurt, Genomics, Mayo Clinic Rochester, nicotine addiction, Nicotine Dependence Center, Research, Science Translational Medicine, vaccine, Wall Street Journal

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