June 8, 2018

Mayo Clinic in the News Weekly Highlights for June 8, 2018

By Emily Blahnik




HealthDay, Many Breast Cancer Survivors Not Getting Needed Mammograms by Steven Reinberg — After surviving a diagnosis of breast cancer, women still need regular screening. But many of them, especially black women, aren't getting the mammograms they need, a new study finds. It's essential to screen for a return of cancer so it can be treated before symptoms appear, the researchers explained. "The use of regular mammograms to detect a return of breast cancer before any symptoms appear is associated with better overall survival," said lead researcher Dr. Kathryn Ruddy, director of cancer survivorship at the Mayo Clinic Cancer Center in Rochester, Minn. Additional coverage: US News & World Report

HealthDay, AHA: Stress Contributes to High Rates of Heart Disease Among Black Adults — Daily stressors are associated with poor health behaviors that put African-American adults at greater risk of heart disease and stroke, a new study finds. The results suggest that primary care doctors, cardiologists and other health care providers should ask their patients about stress to help them identify ways to manage and improve health outcomes, said Dr. LaPrincess C. Brewer, lead author of the Mayo Clinic-led study. "The simple act of recognition of stress in our patients speaks volumes to them," said Brewer, a cardiologist at the Mayo Clinic in Rochester, Minnesota. "[Talking about stress] also fosters a more genuine patient-physician relationship." Additional coverage: American Heart Association News

STAT, Grail’s cancer blood test shows ‘proof of principle,’ but challenges remain by Sharon Begley — There are still years of work before Grail has a cancer blood test ready for clinical use. But the four studies it presented at the annual meeting of the American Society of Clinical Oncology demonstrate “a proof of principle,” said geneticist Fergus Couch of the Mayo Clinic, a co-author of a study using Grail’s system to detect breast cancer. “These methods are better for some cancers than others, and there are some cancers we didn’t pick up. But it bodes well that we can detect cancers and not make many mistakes in terms of telling someone she has cancer when she doesn’t.”

STAT, Why was Theranos so believable? Medicine needs to look in the mirror by Michael J. Joyner —To get some perspective on what happened, I looked back at what was said about the company just a few years ago. I re-read a December 2014 article in the New Yorker on Theranos and its founder, Elizabeth Holmes. What struck me as I compared the “60 Minutes” and New Yorker pieces, which were separated by only a little more than three years, is one simple question that seems to have been missed in the ashes: Why was the Theranos pitch so believable in the first place? — Michael J. Joyner, M.D. is an anesthesiologist and physiologist at the Mayo Clinic. The views in this article are his own.

Wall Street Journal, Doctors Suggest Less Chemo, Surgery for Some Cancer Treatments by Peter Loftus — Drugmakers could face sales pressure if more doctors curtail treatments as a result of new studies, or if insurers start limiting reimbursement...Dr. S. Vincent Rajkumar, a blood-cancer specialist at the Mayo Clinic in Rochester, Minn., and critic of drugmakers’ pricing practices, cautioned that companies could seek to preserve sales by raising U.S. prices to offset reduced usage.

Washington Post, There are some new ways to fight disabling migraines by Erin Blackmore — If you’re living with migraine, there’s another way to get involved: the newly launched American Registry for Migraine Research (ARMR). ARMR collects demographic and health information from each participant, along with an optional blood sample. Available to patients at a handful of facilities including the Mayo Clinic in Phoenix and the Thomas Jefferson University Headache Center in Philadelphia, it’s still new. But the hope is that ARMR will grow into a valuable resource for making treatment more effective.

Reader’s Digest, The Worst Heart Health Advice Cardiologists Have Heard by Jill Waldbieser — "Movies and TV shows often show dramatic portrayals of people clutching their chests, but heart attacks don't always show up that way. And women, in particular, are more likely to experience atypical symptoms. Approximately 40 percent of women will report jaw or shoulder discomfort, sweating, indigestion, or nausea—yet no chest pain or pressure."—Amy Pollak, MD, a cardiologist at Mayo Clinic in Jacksonville, Florida

Daily Mail, What IS that random fatigue twitch that plagues your arms or eyes when you don't get enough shut-eye? by Natalie Rahhal — It always seems to happen when you are already running on too little sleep: your arm or your eye starts twitching spastically, as if you weren't having a hard enough time concentrating.  The subtle jerks could last for two minutes, or two hours, but either way, it feels like an eternity…People get nervous about them but really, they're benign, not pathologic,' in nearly all instances, Mayo Clinic neurologist Dr. Eric Sorenson says… There is an association between twitches and amyotrophic lateral sclerosis (ALS), which has probably caused a second sleepless night for plenty of people suffering the tired twitches.  But in reality, most twitches are normal and harmless, explains Dr Sorenson.

Forbes, Do Alternative Medicines For Alzheimer's Really Work? Does Anything? by Robin Seaton Jefferson — Coenzyme Q₁₀, for example, is all the rage these days. Also known as ubiquinone, ubidecarenone, coenzyme Q, and abbreviated at times to CoQ₁₀, CoQ, or Q₁₀ is an antioxidant found in animals and most bacteria that the body produces naturally. Cells use CoQ10 for growth and maintenance. Mayo Clinic reports that levels of CoQ10 in your body decrease as you age and have been found to be lower in people with certain conditions such as heart disease. The antioxidant is naturally found in meat, fish and whole grains.

Forbes Mexico, 10 consejos para dejar de fumar en forma definitive — Cuando se siente la necesidad de consumir, es importante recordar que el deseo posiblemente pasará luego de 5 o 10 minutos, incluso si es intenso. Y cada vez que la persona resiste el deseo, está un paso más cerca de abandonar el hábito para siempre. Expertos del Centro para la Dependencia a la Nicotina de Mayo Clinic comparten 10 consejos que ayudarán a resistir el deseo de fumar…

Redaccion Medica, Aumentan los problemas de coagulación en la edad pediátrica — Vilmarie Rodríguez, pediatra especialista en hematología y oncología de Mayo Clinic, Rochester, Minnesota, ha adelantado algunos factores de riesgo que se presentan con mayor frecuencia y originan problemas de coagulación en la edad pediátrica.

Prevention, 7 Reasons Your Nipples Hurt by Cassie Shortsleeve — “It’s important to wear a good quality sports bra to reduce movement of the breasts while running,” says Jennifer K. Hazelton, a clinical nurse specialist at the Mayo Clinic’s Breast Diagnostic Clinic. Look for a bra made for your go-to form of activity (running bras tend to have more support) and never wear a new sports bra on race day. If you’re in a great sports bra and still noticing issues? Covering your nipples in Vaseline can reduce friction (and thus pain), she notes.

Post-Bulletin, Week in Photos — Filmmaker Ken Burns, left, talks with Mayo Clinic President and CEO John Noseworthy during a presentation about his documentary about Mayo Clinic on Wednesday, May 30, 2018, at the Siebens Building in downtown Rochester.

Minneapolis/St. Paul Business Journal, Mayo Clinic spinoff Ambient closing in on $1.5M to step up marketing by Katharine Grayson — Health care technology startup Ambient Clinical Analytics Inc. is close to wrapping up a $1.5 million round of funding that will go toward ramping up sales and marketing. The Rochester, Minn.-based company makes technology that analyzes patient data in real time and generates patient-information dashboards for doctors. Additional coverage: American Inno

Twin Cities Business, Mayo Biobank Collaborates with Company Seeking to Identify Alzheimer’s Risk by Don Jacobson — The Mayo Clinic’s Biobank program, fresh off the launch of a nationwide government program to store 35 million donated bio-samples to advance the science of individualized medicine, has now also attracted a private-sector collaboration targeting Alzheimer’s disease. The Mayo Biobank is a collection of blood samples and other health information donated by some 50,000 Mayo Clinic patients since it was established in 2009. It collects samples and health information from patients and other volunteers regardless of health history, making it unique from other, disease-specific biobanks in that regard – and in so also making it singularly useful for researchers working in genomics-based individualized medicine.

Star Tribune, You can grow happiness through focus and practice — Many people wait around for happiness to find them, when, in fact, there are techniques you can use to create a happier and more enjoyable life “Research has shown you have control over your happiness,” said Dr. Stacy Blackburn, a Mayo Clinic Health System family physician. “It all relates back to your personality and also your thoughts and behaviors, which can be changed.”

KARE 11, Gabby Gingras to get her new teeth by Boyd Huppert — Mayo Clinic doctors proposed rebuilding Gabby’s jaw with bone grafts from her hip, into which teeth could be implanted. But, in a denial letter, Aetna called the procedure dental in nature, and therefore not covered by Gabby’s medical insurance. After KARE 11 reported on Gabby’s situation, donors chipped in roughly $45,000 on two GoFundMe pages. The Minnesota Dental Association pledged another $5,000.

Florida Times-Union, Health Notes: Mayo Clinic is considered the place to work according to YouGov BrandIndex — Mayo Clinic, which has campuses in Jacksonville, Arizona and Rochester, Minn., ranked first out of more than 1,600 brands in the 2018 Reputation Rankings by YouGov BrandIndex. Respondents were asked “Would you be proud or embarrassed to work for this brand?” The workforce Reputation Rankings were based on the average reputation scores between May 1, 2017 to April 30, 2018. Scores ranged from -100 to +100. Mayo Clinic earned the top spot with a score of 52.9.

Mankato Free Press, Cancer group calls for earlier colon screenings by Brian Arola — Dr. Stephan Thome, Mayo Clinic Health System in Mankato’s regional oncology medical director, said the Cancer Society’s change will more immediately raise awareness for the importance of screenings. “Even if it takes awhile to find widespread use and reimbursement, I think opening up the conversation that young people can get colon cancer, that awareness alone will lead to earlier diagnosis and potential for more lives saved,” he said. “I think it’s a great first step.”Dr. Matthew Carns, a gastroenterologist at Mankato Clinic, expects the change to spur plenty of screening conversations between patients and doctors. “For pure screening, it’s going to push us to at least have the conversation to see if they have interest in the screening,” he said.

Wisconsin State Journal, Exact Sciences, Mayo Clinic say they've developed blood test for liver cancer by Judy Newman — Exact Sciences Corp. and the Mayo Clinic say they’ve developed a blood test that correctly identified 95 percent of the cases of a common form of liver cancer. The news, released Tuesday in a presentation at a major conference of gastroenterologists, is a signal that the liver cancer blood test could be the second product that Exact, of Madison, and Mayo, of Rochester, Minnesota, will seek to bring to market, following Cologuard, their stool-based test for colorectal cancer. The liver cancer blood test could be available in about three years if all goes well, Exact CEO Kevin Conroy said. But it’s just the start. Mayo clinic physician John Kisiel said Mayo and Exact are working on identifying biomarkers for the top 16 killer cancers. Additional coverage: Fierce Biotech, Science Daily

WKBT La Crosse, CPR & AED Awareness Week highlights importance of knowing how to save a life — This week is national CPR and AED awareness week, a time to highlight how lives can be saved if more people knew CPR and how to use an Automatic External Defibrillator. Doctors with Mayo Clinic Health System in La Crosse say training for both CPR and the use of AED'S is crucial for saving lives as every minute can mean the difference between life or death…."We have a group of volunteers from Tri-State Ambulance, local fire departments, Stoddard, La Crosse, Onalaska, from Gundersen Health System, from Mayo Clinic Health System, and we just send out an email and say hey who can help out this group and then one of us will come," said Marlis O'Brien of Mayo Clinic Health System.

WEAU Eau Claire, Appointments no longer needed for urgent care at Mayo Clinic Health System in Eau Claire by Ruth Wendlandt — Patient appointments are no longer needed at one local health clinic. Urgent Care at Mayo Clinic Health System in Eau Claire says it is now taking walk-ins only to provide patients with same-day care. The director of Urgent Care, Shannara Faupl, says, "having access to same-day care has the potential to save patients from having to make a more costly emergency room visit." Urgent Care on West Clairemont Avenue is open seven days a week.

WXOW La Crosse, Testing the water on a dragon boat by Peter Lenz — Every year since 2013 Mayo Clinic Health System, along with The Boys and Girls Club of Greater La Crosse, host the Big Blue Dragon Boat Festival. On Sunday, people had a chance to see what being on a dragon boat team was all about. The "Try It Free" event provides everything needed to hop into a boat and start paddling. With an experienced racer leading the team it's a great way to get your feet wet while getting some physical activity.

WXOW La Crosse, Wisconsin Health Atlas releases obesity map by Amber Meyer — La Crosse health officials say there are ways to combat the higher obesity rates, even when your summer schedule starts to become hectic. "We do have the opportunity to maybe pack more picnic lunches or picnic suppers, where the choices can be made at home," said Dr. Charles Peters, a pediatric consultant for the Mayo Clinic Health System. "[Those] choices can be, shall we say, healthier, more nutritious, and better balanced."

WXOW La Crosse, Local oncologists react to new breast cancer treatment findings by Mackenzie Amundsen — One oncologist from Mayo Clinic Health System calls the findings "practice changing." "Up until now,we had clarity in terms of what to do with the patients who were low risk. If you have a low risk disease, you don't give them chemotherapy. You just give them endocrine therapy," said Dr. Asad Javed. "There was clarity in terms of what to do with a high-risk patient. If they are high risk, give them chemotherapy. There is no doubt about that, but it was intermediate risk that the study has specifically looked at which is where the gray zone of decision making was."

WKBT La Crosse, La Crosse Logger baseball game celebrates survivors by Alex Fischer — Mayo Clinic Cancer Center director of nursing and patient care Rachel Bishop said, “This is our second year of doing Celebrate Life at The La Crosse Loggers. We’re really just celebrating anyone who cancer has touched their life. They could be a survivor; they could be going through treatment right now, but – just anybody who’s been touched by cancer.”  The event is a collaboration between Gundersen Health System and Mayo Clinic Health System.

Cardiovascular Business, Testosterone-estrogen ratio signals CVD risk in post-menopausal women by Daniel Allar — In a related editorial, Virginia M. Miller, PhD, and Rekha Mankad, MD—both with the Mayo Clinic Women’s Health Research Center in Rochester, Minnesota—proposed adding genetic testing to the equation to further personalize care. “Individual variability in hormone profiles among women may reflect genetic variation in one more of the enzymes involved in steroid metabolism, and thus, the bioavailability of testosterone and estradiol,” they wrote. “Defining cardiovascular risk for women should account for individualized profiles of genetic variants in enzymes associated with steroid metabolism, uptake, and receptors in conjunction with risk for specific cardiovascular pathologies. This approach is precision medicine.”

Tech Times, Drug That Can Prevent Migraine Without Significant Side Effects Shows Promise In Clinical Trial by Allan Adamson —David Dodick, from Mayo Clinic in Phoenix, Arizona, and colleagues reported in JAMA Neurology on May 29 that the experimental drug Galcanezumab reduced in half the number of days most patients suffered from a migraine in a month. In the trial involving 858 patients who have a history of four to 14 migraines per month, the researchers found that monthly migraine days among those who received galcanezumab were reduced by 4.7 days. Monthly migraine days among the participants who received placebo were reduced to just 2.8 days.

Healthline, New Drug May Stop Migraine Headaches Before They Start — “Aimovig blocks the ability of a protein known as calcitonin gene-related peptide (CGRP) to initiate a migraine attack. Based on clinical trials, blocking CGRP activity is effective in reducing migraine attack frequency. In the clinical trials for Aimovig, one out of two patients had at least a 50 percent reduction in the number of days with migraine each month, over a six month period,” Dr. Amaal Starling, a neurologist and migraine specialist at the Mayo Clinic in Arizona, told Healthline.

Bustle, What’s The Difference Between A Food Allergy & Sensitivity? 7 Signs You’re Intolerant, Not Allergic by JR Thorpe"A true food allergy," says the Mayo Clinic, "causes an immune system reaction that affects numerous organs in the body... In some cases, an allergic food reaction can be severe or life-threatening. In contrast, food intolerance symptoms are generally less serious and often limited to digestive problems."

Express UK, UK weather: What happens when lightning strikes a HUMAN? What is a lightning tree? by Amani Hughes — Eric Grube, Director at Mayo Clinic in Wisconsin, exclusively told Express.co.uk: “A number of different health issues can occur when you get struck by lightning. “The most obvious of course are burns throughout your body. Other initial factors to consider as an emergency physician we look at would be tissue damage and cardiac arrhythmia.”

Express UK, Diabetes type 2 symptoms: Six snacks you can eat before bed by Luka Andrews — It may be possible to reverse your diabetes by trying these steps. Answering for the Mayo Clinic, Regina Castro, based in the US, says that diabetics can eat these snacks before going to bed. “If you have diabetes, late-night snacks aren’t necessarily off-limits, but it’s important to make wise choices,” says Castro. “Late-night snacks add extra calories, which can lead to weight gain. “And if you snack after your evening meal - especially if the foods contain carbohydrates - you may wake up the next morning with a high blood sugar level.”

Romper, Stats On Infertility In Millennials Show Just How Complicated The Issue Is by Vanessa Taylor — Discussions around infertility often exclude those experiencing what's known as secondary infertility. The Mayo Clinic describes secondary infertility as the "inability to become pregnant or to carry a baby to term after previously giving birth to a baby."

Ozarks First, Host Chat: Mayo Clinic Cookbook by Shelby Styron — Deb Balzar is interviewed on the Mayo Clinic cookbook. Starts at 4:30.

Yahoo! Sports, Jake Diekman didn't let life-altering surgery keep him away from baseball field by Chris Cwik — Two offseasons ago, Diekman’s ulcerative colitis — a chronic disease of the colon that impacts over 900,000 Americans — flared up around Thanksgiving. He tried to get it under control, but the issue lingered into December. At that point, he let the Rangers know something was up and they recommended he see a doctor at the Mayo Clinic.

Atlanta Journal-Constitution, News flash about hot flashes: They can last longer than you think — Menopause symptoms are not just for midlife anymore, according to a new Mayo Clinic study published this month in the Journal of the North American Menopause Society. The study, conducted by researchers at Mayo Clinic gathered data from nearly 5,000 women. When asked whether they experienced any symptoms commonly associated with menopause, such as hot flashes and night sweats (vasomotor symptoms), a significant percentage reported having them well into their 60s, 70s and 80s.

Healio, Alfuzosin decreases anal pressure in women with constipation — Alfuzosin, an alpha1 receptor antagonist, helped decrease anal pressure in women with constipation, according to data from a study presented at Digestive Disease Week. “We know that some patients with defecatory disorders have high anal resting pressure,” Subhankar Chakraborty, MD, of the Mayo Clinic in Rochester, Minn., said in his presentation. “While alpha1 antagonists are used to treat urinary symptoms in benign prostate hyperplasia, their role in the treatment of defecatory disorders has not been explored.”

Healio, Artificial intelligence identifies long QT syndrome when ECG did not — Michael J. Ackerman, MD, PhD, director of Mayo Clinic’s Genetic Heart Rhythm Clinic and the Windland Smith Rice Sudden Death Genomics Laboratory at Mayo Clinic, and colleagues investigated whether AI using deep neural networks is better than QTc alone at identifying patients with concealed long QT syndrome. The researchers applied AI to data from lead one of a 12-lead mobile ECG (KardiaMobile and KardiaBand, AliveCor).  They analyzed ECGs from 1,048 patients with long QT syndrome and 1,010 patients initially identified as normal. The derivation cohort consisted of 72% of patients, with the rest comprising the validation cohort.

Healio, IL-15 inhibitor among key celiac research at DDW 2018 — In this exclusive video, Joseph Murray, MD, of the Mayo Clinic in Rochester, Minn., shares an overview of key research and discussions in celiac disease being shared at Digestive Disease Week. “Of particular interest are two trials that are being reported using a novel agent that blocks interleukin 15,” he said. “It’s been known now for a few years that interleukin 15 is crucial to the damage that occurs in celiac disease, especially in refractory celiac disease, and we’re going to hear the exciting results of really the largest study ever conducted on refractory celiac disease, and that’s with this new agent AMG-714.

Healio, Diagnosis changes occur in 30% of repeat gastric emptying tests — One-third of patients undergoing scintigraphy will exhibit different results when repeated, prompting a need for repeat tests in those who do not have markedly reduced gastric emptying, according to a presenter at Digestive Disease Week 2018. “Among participants with upper GI symptoms, assessment of GE with scintigraphy is relatively reproducible, however in 30% of patients, the diagnosis changed between the first two studies,” Anshuman C. Desai, MD, of the Mayo Clinic, Rochester, Minn., said during his presentation. “It may be prudent to reassess gastric emptying before labeling a diagnosis of gastroparesis with a less pronounced delay in gastric emptying.”

Healio, Relapse after LT for alcoholic liver disease more common in younger patients — Relapse to alcohol use after liver transplantation for alcoholic liver disease was more common among younger patients, according to a study presented at Digestive Disease Week 2018. “Alcoholic liver disease is the second most common indication for liver transplant,” Mohanad Turki Ali Al-Qaisi, MD, from the Mayo Clinic in Phoenix, Ariz., said in his presentation. “Timing of alcohol relapse after LT can have a detrimental impact on patient survival.”

Healio, Undiagnosed celiac disease more common in women — Claire L. Jansson-Knodell, MD, of the Mayo Clinic, in Rochester, Minn., said that while previous studies have suggested that diagnosed celiac disease is more prevalent in women, there has been a lack of studies that have focused on sex-based differences in undiagnosed populations. “There is a known female predominance in diagnosed celiac disease,” Jansson-Knodell said in a presentation. “What is unknown is if that [sex] disparity extends to undiagnosed or undetected populations identified through screening studies.”

Villages Daily Sun, Cancer survivors find support, strength, hope by Greg Williams — Daniel Bard, of the Village Mira Mesa, leads a prostate cancer support group at Laurel Manor Recreation Center. A 22-year survivor of prostate cancer, Bard builds upon his experiences in his role as facilitator for the 300-member local group, and elsewhere around the country. “Detect it early enough and you can live a long, productive life,” Bard said. His initial surgery, in 1996, was at Mayo Clinic in Rochester, Minnesota. He since has undergone several follow-up treatments, currently receiving monthly doses of a hormone therapy drug. Bard encourages patients to learn about their particular cancer, so they can have informed discussions with their doctors about the latest treatment options.

Finance & Commerce, Sustainable: Plugging energy into construction planning by Frank Jossi — On Mayo Clinic’s campus in Rochester, one of the first health care buildings in the country to use “performance-based procurement” has begun to take shape. Performance-based procurement makes energy efficiency a priority in planning new buildings. In the case of the 155,000-square-foot addition to the Generose Building on Mayo’s St. Marys campus, planners applied principles of performance-based procurement to establish energy-consumption standards for the completed project. Ken Potts of Mayo’s Facilities Project Services says the clinic wants to reduce energy consumption in existing and new buildings, so performance-based procurement makes sense. “It’s a new approach industrywide,” he said. “Mayo has looked at energy conservation in many ways over the years. … Performance-based procurement is another arrow in the quiver.”

Healthline, FDA Drug Approval May Make Life Easier for People with Ulcerative Colitis — “The drug tofacitinib has been used to treat rheumatoid arthritis. Now, it can be administered to people with this specific type of inflammatory bowel disease…It’s highly effective,” Dr. Edward V. Loftus Jr., a professor of medicine in the division of gastroenterology and hepatology at the Mayo Clinic in Minnesota, said while speaking on behalf of the American Gastroenterological Association. “However, we don’t have any comparative effectiveness studies, so it’s hard to say how much more or less effective relative to other therapies,” he told Healthline.

MedPage Today, White Matter Lesions May Be Partially Reversible in RCVS by Judy George — Recurrent thunderclap headache -- a headache reaching a 10 out of 10 pain level in less than 60 seconds -- is "a red flag for RCVS," noted Amaal Starling, MD, of the Mayo Clinic in Phoenix, who was not involved in the study. "RCVS is a secondary headache disorder that can result in significant morbidity with posterior reversible encephalopathy syndrome, stroke, and intracranial hemorrhage," Starling told MedPage Today. "Better characterization of white matter hyperintensities may lead to more rapid and accurate diagnoses and may provide a better understanding of the pathogenesis of RCVS."

MedPage Today, Bezafibrate Normalizes Liver Enzymes in PBC by Nicole Lou — Findings from the study were first reported at the 2017 International Liver Congress, the annual meeting of the European Association for the Study of the Liver. "These results merit cautious excitement. Bezafibrate is the first drug to show improvement in biochemical liver measures and measures of fibrosis and a reduction in symptom burden," commented Elizabeth Carey, MD, of Mayo Clinic in Phoenix, in an accompanying editorial. "PBC remains an incurable disease," she wrote. "In the past two decades, it has become apparent that approximately 40% of patients with PBC do not have an adequate biochemical response to ursodeoxycholic acid."

Atlanta Journal-Constitution, Why antacids — not an inhaler — may be the key to treating asthma — Asthma is a relatively common lung problem, usually caused by allergies, heavy exercise or chemical exposure in the workplace. But Dr. Alexei Gonzalez Estrada, a Mayo Clinic allergy and immunology specialist, says most people don't realize heartburn could be making their asthma worse. "And what happens is you have inflammation of your airway tree, Gonzalez Estrada says. Think of your lungs and airway as an upside-down tree. "And what happens is it gets full of gunk, and that's when people get wheezing, shortness of breath, chest tightness."

Science News, What we know — and don’t know — about a new migraine drug by Leah Rosenbaum — The new drug, Aimovig, generically called erenumab, is a type of monoclonal antibody treatment, a class of medications that resemble the antibodies that the body naturally produces to bind to infectious pathogens…The drug can take some time to clear the body, so women who are trying to conceive and don’t want Aimovig in their system should discontinue treatment at least five months before becoming pregnant, says neurologist David Dodick of the Mayo Clinic in Phoenix. Dodick participated in the design and analysis of the Aimovig clinical trials.

Bustle, Work Stress Is Associated With Heart Rhythm Disorder Risks, According To A New Study by Callie Tansill-Suddath — The Mayo Clinic describes atrial fibrillation (or A Fib) as a defect that affects a person's cardiac rhythm. It causes a person's heartbeat to be irregular, and often rapid. The heart has four chambers: two ventricles, and two atria. Per the Mayo Clinic, during atrial fibrillation, the heart's two upper chambers (the atria) beat erratically, and out of sync with the two lower chambers (the ventricles). Ultimately this can lead to blood clots and even strokes.

WBUR, A Bike Accident Left This ER Doctor Paralyzed. Now He's Back At Work by Jeremy Hobson and Chris Bentley — Monday mornings are one of the busiest times of the week in the emergency room at the Mayo Clinic in Rochester, Minnesota. On one Monday in May, a middle-aged man tells Dr. Daniel Grossman he's been feeling weak and having heart palpitations. After a few more questions, the doctor recommends some blood work, and pulls open the curtain to head back to the ER. It's a typical doctor-patient interaction, but one thing is unusual: Both the patient and the doctor are in wheelchairs — the patient because he's visiting the emergency room, and the doctor because of a spinal cord injury. Grossman, 37, lost the use of his legs less than a year ago, and he's already back at work.

AccuWeather, EpiPen shortage in US a threat for those who suffer from bee allergies by Jennifer Fabiano — If a patient realizes that their EpiPen has expired, they can switch to a different device during the shortage but should consult with their doctor first, according to Martha Hartz, the chair of Pediatric Allergies at Mayo Clinic. There are various epinephrine auto-injectors. Epinephrine is another term for adrenaline, which is the first line emergency treatment for severe allergic reactions, including anaphylaxis, according to Mayo Clinic. While EpiPen is the most commonly prescribed auto-injector, Auvi-Q and Adrenaclick are other common devices, according to Hartz.

Medscape, Anticholinergic Avoids Pacemaker in Case of AF With Bradycardia by Fran Lowry — Hyoscyamine, an anticholinergic drug, may allow some patients who would otherwise require a pacemaker for slow ventricular response during atrial fibrillation (AF) to avoid it, a case report suggests.   "To our knowledge, this is the first report of hyoscyamine or any other anticholinergic drug being used to avoid pacemaker placement in a patient with symptoms caused by a slow ventricular response during atrial fibrillation," write Scott A. Helgeson, MD, and colleagues from Mayo Clinic, Jacksonville, Florida.

WBTV, NASCAR announces plans to use new concussion test by Ashley Stroehlein — A new NASCAR rule will require all drivers to complete baseline concussion tests if they haven’t already done so. This test will be used to help diagnose drivers with concussions after a serious incident. Earlier this year, the sport announced that it will use the King-Devick test to evaluate drivers for concussions. This test, developed with the help of the Mayo Clinic, focuses on eye movement. Subjects are given a card and asked to read the numbers on the card as quickly as they can without any errors.

Medical Design & Outsourcing, More information out about One Discovery Square near Mayo Clinic by Chris Newmarker — Slated to open in April 2019, the four-story building is meant to be the first step in the creation of an innovation campus that will eventually encompass 2 million square feet. Discovery Square is part of the 20-year Destination Medical Center project, in which $585 million in state and local government infrastructure funds are expected to leverage about $5 billion of private investment in Rochester. Mayo Clinic will occupy a third of the building, with the clinic’s anchor tenants including advanced radiologic technology, advanced laboratory diagnostic medicine and regenerative medicine, Dr. Clark Otley, medical director of the Dept. of Business Development at Mayo, told Medical Design & Outsourcing last month.

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