September 27, 2018

Drug cocktail could extend your life, killing cells related to aging

By Karl W Oestreich

CNBC
Dr. James Kirkland, Mayo Clinic's Center on Aging director, joins 'Squawk Box' to discuss his new drug, research involving senolytic cells and CNBC logohow they combat age-related diseases.

Reach: CNBC is a 24-hour cable television station offers business news and financial information. The channel provides real-time financial market coverage to an estimated 175 million homes worldwide. CNBC offers in-depth and breaking news coverage, focusing on politics, business, finance and entertainment. Programming includes live ongoing coverage of daily stock market activity, breaking business news, and in-depth interviews with top business analysts and executives. The network also features an extensive array of talk-based entertainment programming featuring prominent celebrity guests and business leaders. The network has 9,500,000 monthly viewers in US and Canada.

Additional coverage:
Forbes, Could Senolytic Therapies Cure Aging?

Context: The presence of senescent or dysfunctional cells can make young mice age faster. And using senolytic drugs in elderly mice to remove these rogue cells can improve health and extend life. These findings from Mayo Clinic researchers and collaborators provide a foundation on which to move forward in this area of aging research. The results appear in Nature Medicine. “We can say with certainty that senescent cells can cause health problems in young mice, including causing physical dysfunction and lowering survival rates, and that the use of senolytics can significantly improve both health span and life span in much older naturally aged animals,” says James Kirkland, M.D., Ph.D., a Mayo Clinic geriatrics researcher who heads Mayo Clinic’s Kogod Center on Aging. Dr. Kirkland is senior author of the study. You can read more about the research on Mayo Clinic News Network.

Contact:  Bob Nellis, Traci Klein

Tags: aging, CNBC, Dr. James Kirkland, senescent cells, senolytic drugs, Uncategorized

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