April 5, 2019

Mayo Clinic in the News Weekly Highlights for April 5, 2019

By Emily Blahnik

Wall Street Journal, What AI Can Tell From Listening to You by John McCormick — The Mayo Clinic conducted a two-year study that ended in February 2017 to see if voice analysis was capable of detecting coronary-artery disease. Every person’s voice has different frequencies that can be analyzed, explains Amir Lerman, director of the Cardiovascular Research Center at Mayo. Mayo, in collaboration with voice-AI company Beyond Verbal, used machine learning to identify what it thought were the specific voice biomarkers that indicated coronary artery disease. The clinic then tested groups of people who were scheduled to get angiograms. Everyone in the study recorded their voices on a smartphone app, and the recordings were analyzed by Beyond Verbal. The finding: Patients who had evidence of coronary-artery disease on their angiograms also had the voice biomarkers for the disease. Dr. Lerman says Mayo is hoping to deploy the technology in the near future. “I think it’s just an amazing area that opens new doors into how we treat patients,” he says.

USA Today, Can using organic tampons and pads make your period shorter? by Rasha Ali — Dr. Daniel M. Breitkopf, an Ob/Gyn at the Mayo Clinic, doesn't think organic pads can alter the flow of a period or shorten a cycle, but there could be an explanation for organic tampons doing so. "The device is going into the body so that could change things, but there's no scientific evidence that's the case," Breitkopf tells USA TODAY. The Mayo Clinic doctor also cited recall bias to explain why some women seemed to think organic products made their cycles shorter. "Menstruation can change naturally from month to month," he says. "Stress affects menses and that’s probably the biggest thing from a month-to-month or year-to-year basis, but menses also changes closer to menopause."

New York Times, Why Don’t More American Men Get Vasectomies? by Christina Caron — Every year, men schedule their vasectomies in conjunction with the N.C.A.A. men’s basketball tournament, so they can watch the games while recovering on the couch with a frozen bag of peas. In fact, at the Mayo Clinic in Rochester, Minn., so many men sign up for vasectomies during March Madness that appointments reach “max capacity,” said Dr. Tobias S. Kohler, a urologist and men’s health expert at the medical center who has observed this phenomenon ever since he was an attending physician a decade ago.

New York Times, Brain Booster in a Bottle? Don’t Bother by Jane E. Brody — …Of course, supplements are only one of several arms of the memory-enhancing industry. There are also myriad videos, games, puzzles, programs and what-have-you currently being marketed. None of these are a problem if people have fun doing them as long as they don’t ignore measures far more likely to reduce the risk or delay the onset of dementia. Some of these products may even be helpful up to a point. Researchers at the Mayo Clinic in Phoenix reported in JAMA Neurology two years ago that older people who engage in mentally stimulating activities like games, crafts and computer use have a lower risk of developing mild cognitive impairment, often a precursor to dementia. The researchers, led by Dr. Yonas E. Geda, a psychiatrist and behavioral neurologist at Mayo, followed nearly 2,000 cognitively normal people 70 or older for an average of four years. After adjusting the results for sex, age and education level, they found that computer use decreased the participants’ risk of cognitive impairment by 30 percent, engaging in crafts decreased it by 28 percent and playing games decreased it by 22 percent. Dr. Geda said that those who performed such activities at least once or twice a week experienced less cognitive decline than those who did the same activities at most only three times a month.

Washington Post, Matthew Stafford’s wife needs surgery to remove brain tumor by Matt Bonesteel — Kelly Stafford, wife of Detroit Lions quarterback Matthew Stafford, announced Wednesday on Instagram that she needs surgery to remove a tumor on her brain. After experiencing a number of instances of vertigo, Kelly Stafford said the Lions team physician advised her to get an MRI exam, which revealed the tumor and the need for the surgery…According to the Mayo Clinic, acoustic neuroma refers to a noncancerous, slow-growing tumor that develops on the nerve leading from the inner ear to the brain. Surgery “involves removing the tumor through the inner ear or through a window in your skull” while taking strides to preserve “the facial nerve to prevent facial paralysis and preserve hearing when possible.”

STAT, In N.Y., a drastic response to a measles outbreak tests trust in government by Lev Facher — …Amid indications that three measles outbreaks in the U.S. have been tied to cases from Israeli travelers recently, Jewish leaders and partner health organizations are trying to get the message out. This week, Refuah flew Dr. Robert Jacobson — a Mayo Clinic pediatrician known for his work overcoming “vaccine hesitancy” — to Rockland County to train its staff. Some Orthodox leaders, meantime, have issued a Hebrew-language notice declaring that religious leaders say it’s mandatory that children be vaccinated against measles.

AARP, More Detailed Mammography Results on the Way by Christina Ianzito — When women get mammogram results they would also get information about the density of their breast tissue under a new proposal from the Food and Drug Administration, the first change to federal mammography standards in 20 years...About half of all women have dense breast tissue. Although dense breasts are more common in younger women, says Deborah Rhodes, an internist and breast cancer researcher at the Mayo Clinic, “some women retain it well into their 70s and 80s.”

Kaiser Health News, Elite Hospitals Plunge Into Unproven Stem Cell Treatments by Liz Szabo — Doctors at the Mayo Clinic try to provide stem cell treatments and similar therapies responsibly, Shapiro said. In a paper published this year, Shapiro described the hospital’s consultation service, in which doctors explain patients’ options and clear up misconceptions about what stem cells and other injections can do. Doctors can refer patients to treatment or clinical trials. “Most of the patients do not get a regenerative [stem cell] procedure,” Shapiro said. “They don’t get it because after we have a frank conversation, they decide, ‘Maybe it’s not for me.’”

CNN, New drug represents 'paradigm shift' in treatment of acute myeloid leukemia by Susan Scutti — Dr. Mrinal Patnaik, a hematologist at Mayo Clinic said the study results and FDA's approval of gilteritinib are "very encouraging." "I trained in the early 2000s, when there was not a single oral agent for the management of AML," said Patnaik, who was not involved in the new study. "One of my professors had told me that AML was akin to a warlike situation where sometimes, you had to bomb the village in order to save it. We would throw these drugs that would kill everything and hope patients would recover with normal bone marrow." In the past two years, at least four new personalized medicines targeting key genes have "given patients much better outcomes and have changed the landscape of how we manage acute leukemia," he said. It's a "paradigm shift." Additional coverage: KXLH Montana

CNN, Using blood, saliva, urine to detect cancer: Scientists' 'holy grail' by Jacqueline Howard — Scientists at Mayo Clinic and a cancer diagnostics company called Exact Sciences have been collaborating on research to identify specific proteins or biomarkers tied to various tumor types. The idea is that if those biomarkers can be found in blood, they could be used to diagnose tumors in various areas of the body. "We have identified biomarkers for 13 of the top 15 cancers," including breast, colorectal and liver cancers, said Dr. Paul Limburg, a gastroenterologist at Mayo Clinic in Rochester, Minnesota, and co-chief medical officer of Exact Sciences. Yet more work is needed before those biomarkers could be used to detect and diagnose cancers in patients at early stages. "While more of the puzzle is being pieced together from a scientific perspective, it will still take years to conduct and complete the rigorous clinical research necessary to put these tests into everyday practice," Limburg said. Additional coverage: WNEM Michigan

TIME, Women Die From Heart Attacks More Often Than Men. Here’s Why — and What Doctors Are Doing About It by Barbara Sadick — Dr. Sharonne Hayes, founder of the Mayo Clinic Women’s Heart Clinic, says that in the late 1980s when she was in cardiology training, she was taught that heart disease was very uncommon in women. Several large heart-disease studies excluded women, and it wasn’t until the Women’s Health Initiative began in 1991 that it started to become clear that the body of knowledge that did exist was applicable mostly to men. Sometimes that knowledge worked when applied to women, and sometimes it didn’t. Numerous studies conducted in the 1980 and 1990s didn’t specifically exclude women but often had requirements that made the sample group overwhelmingly male, like excluding women of reproductive age. Additionally, many studies wanted people with few or no additional diagnosed medical problems, and women tend to have more than men.

Prevention, How Stress Hits Women’s Brain’s Harder—and Why Men Don’t Always Get It by Jennifer L. Cook — Aspects of the brain’s design that served us well thousands of years ago now make us susceptible to negative emotions and mental fatigue, both of which ratchet up our stress, says Amit Sood, MD, professor of medicine at the Mayo Clinic and founder of the Mayo Clinic Resilience Program. Although our brains have evolved over time, “the speed of life today is the main stressor—it’s much faster than our brain’s ability to adapt,” he says. And that means we often end up with too little time and too few resources to address what life throws at us each day, which adds to a diminishing sense of control over our lives. Perceived lack of control has been shown to be a huge source of stress.

Telegraph, Alzheimer’s disease may affect twice as many people as estimates suggest by Sarah Knapton — Alzheimer’s disease probably affects twice as many people as current estimates suggest but sufferers are yet to show symptoms, experts believe. Scientists at The Mayo Clinic in Minnesota have been reevaluating the prevalence of the disease using brain imaging to give a definitive answer as to how many people are actually affected. In Britain it is thought around 850,000 people have the disease, but most are diagnosed through clinical assessments when they are already showing symptoms.

Telegraph, The wonder drug that could reverse the ageing process by Sarah Knapton — Sarah Knapton visits the Mayo Clinic to report on how US scientists are trialling senolytics, which target the zombie cells that cause age-related diseases With its pudgy body, tired eyes and hair loss, the lower mouse could easily be the father of the sprightly and alert animal nestling alongside. But they are actually the same age, the result of extraordinary trials of drugs which are slowing down or even reversing the ageing process. Scientists now believe that ageing itself is responsible for many major conditions such as Alzheimer’s, Parkinson’s, arthritis, cancer, heart disease, and diabetes. And they think they have found a way to turn it off. Additional coverage: Daily Mail

Telegraph, Can't wait for the anti-zombie cells drug? Here's how to slow the ageing process today by Maria Lally — The term ‘anti-ageing’ has become synonymous in recent years with luxuriously scented face creams that promise to fight the signs of ageing. But what if a new drug could reverse the significantly more serious side effects of getting older? Earlier this week, my colleague Sarah Knapton visited the Mayo Clinic in the US to report on how scientists there are trialling senolytics: anti-ageing drugs that can slow down and even reverse the ageing process, in a bid to ward off diseases like Alzheimer’s, cancer, heart disease and diabetes.

Post-Bulletin, Investments continue to increase by Randy Petersen — With the goal of encouraging more than $5.6 billion in private investment in 20 years, some define Destination Medical Center by the numbers, rather than by designs and concepts. To achieve the DMC goals, Mayo Clinic plans to invest $3.5 billion in Rochester and hopes to spur $2.1 billion in additional private investment. The legislation that created the effort commits up to $585 million in public spending, all of which will be used on expenses related to public infrastructure and project management. The anticipated state and county contributions have shifted slightly from the estimated expenses in the first years, but the total public expense target remains the same.

Post-Bulletin, A list of coming attractions by Jeff Kiger —There are many development projects in the pipeline in Rochester. Here are a few of them: Mayo Clinic/Pontiac Land Group hotel — Mayo Clinic announced in September a “joint venture” with the Singapore development firm Pontiac Land Group to build a hotel plus clinic floors on top of Mayo’s Gonda Building in downtown Rochester.

Post-Bulletin, Mobility hubs will contribute to mode shift by Randy Petersen — Do you doubt whether the Destination Medical Center initiative can actually achieve its goal of shifting commuter practices? Lisa Clarke says she understands. “People want to get from Point A to Point B and they want to rely on some type of transportation to get them there,” the DMC Economic Development Agency executive director said. “Right now, we are a very car-centric city, because you can rely on your car because you’re the driver.”

Post-Bulletin, Rochester airport, DMC fuel each other by Jeff Kiger — From the very beginning, advocates of the Destination Medical Center initiative repeatedly said that growth of the Rochester International Airport was needed to support DMC. “The airport has long been an invaluable local asset and its role will be even more significant as DMC continues to evolve,” said Lisa Clarke, executive director of the DMC Economic Development Agency, in 2018. The challenge to grow Rochester was that, since the 1970s, more and more area people had been choosing to fly in and out of the Twin Cities than the local airport.

Post-Bulletin, Downtown Rochester's recent additions by Jeff Kiger — Gonda Building: Mayo Clinic started construction of the Gonda Building at 200 First St. SW in 1998. Mostly funded by gifts from the Gonda family, the now 21-floor building was estimated to cost $300 million. It was completed in 2001.

Post-Bulletin, Got an hour to kill? Do it without emptying your wallet by Katie Lauer — Mayo Clinic is known for its world-renowned health care, but it also has an art collection to match. Notably, Mayo has a few selections from pop art extraordinaire Andy Warhol. Ten prints of Flowers are housed within the Mayo Building subways, while nine prints from his Endangered Species series hang on the ninth floor of the same building. The tenth, depicting a bald eagle, can be seen on the first floor of the Siebens Building. If you’re up for an adventure, these works are just the beginning of Mayo’s collection, including a piece from the sculptor behind “The Thinker.

Post-Bulletin, DMC: What about us? Journey to Growth by Matthew Stolle — Each workday, some 45,000 to 50,000 people come from surrounding areas to work in Rochester. It is a daily reminder of Mayo Clinic’s and Rochester’s economic importance. Both are critical to the region’s success. The Legislature’s passage of Destination Medical Center, a $5.6 billion economic development initiative, in 2013 only underscored its king-of-the-hill status. But six years later, DMC-fueled growth has added urgency to a new question: What about the rest of Southeastern Minnesota? What about the area’s cities and towns? Are they to be mere bit players and adjuncts to Rochester and Mayo? Or does DMC’s potential for attracting people and talent create opportunities for surrounding communities?

Post-Bulletin, UMR looks to spread its influence by Matthew Stolle — As Rochester and Mayo grow, fueled by the $5.6 billion Destination Medical Center economic development initiative, UMR is looking to be both opportunistic and strategic in its growth. Locating classrooms and student labs in One Discovery Square proved “great for our students because of the proximity to researchers and industry,” Carrell said. In the coming years, UMR will be looking for more housing and faculty space as well as classroom space, as it grows from a school of 700 students into one of 2,500 students. A lot is being discussed and explored but not settled on yet in this fluid situation.

Post-Bulletin, Norton: Communication remains key for DMC efforts by Randy Petersen — When Kim Norton was elected Rochester mayor in November, voters also gave her a seat on the Destination Medical Center Corp. board….How can more of Rochester become involved or see a benefit?...It’s a difficult thing to address. This was an economic development package. It was the result of primarily interviews with staff and patients at Mayo Clinic, and it was meant to solve some of that dilemma that people who stay here longer need more to do. I see it as something bigger than that. You are fundamentally changing the core of a community, and it really also needs to be good for the community. How you communicate that is always a challenge, and as DMC rolls out … if it’s done well and you activate it as it becomes available, so people come down, see it and become a part of it, that’s maybe more of an opportunity.

Post-Bulletin, Mayo Clinic puts its name on ambulance service by Jeff Kiger — A familiar name will soon be on the sides of ambulances across southeastern Minnesota and Wisconsin. Mayo Clinic Ambulance is replacing the Gold Cross Ambulance name on the fleet of 70 emergency vehicles that serve 120 communities, including Rochester, Albert Lea, Austin, St. Cloud, Duluth/Superior and others. While Mayo Clinic has owned Gold Cross Ambulance service since 1994, many people didn’t realize the connection, said Dr. John Wald, a member of the Mayo Clinic Ambulance Service board of directors. Additional coverage: Duluth News Tribune, FOX 47, WKBT La Crosse, Austin Daily News, Albert Lea Tribune, Business North, KNUJ-Radio, MedCity Beat, Mankato Free Press,  KEYC Mankato, KDAL-Radio, KAAL, KTTC

KAAL, Live Mannequins Bring Awareness to Limb Loss — Dr. Mark Christopherson with Mayo Clinic said many patients are hesitant to get an amputation. "Often the concern is a myth because I want to go hunting again or I want to drive a car. We can explain to them that we fully intend for you to be able to ambulate, possibly hunt again, certainly you'll be able to drive a car,” he said. With modern prosthetic devices, he said people can do their daily routine. "We're a little more aggressive in the sense of training and equipping people and setting their goals high to be active and resume their goals in society right from the beginning," he said.

KAAL, Praying for Gabby's Next Challenge: Overcoming Intense Cancer Treatments — ABC 6 News has been following the story of baby Gabby Brown for months. The one-year-old was diagnosed with AML Leukemia fall of 2018, and people across Southern Minnesota have been rallying around her and her family. This week, Gabby’s parents, who own Estelle’s Eatery and Bar in Harmony, received some difficult news. In a Facebook update, Gabby’s dad Matthew Brown shared that Gabby did not respond well to her fourth round of chemotherapy. He said Friday she was readmitted to Mayo Clinic for an even more aggressive type of chemo. That day, billboards popped up around Rochester with Gabby’s picture and the hashtag “#GabbysGotThis”.

KIMT, Evictions up by 60 percent in Olmsted County by Maleeha Kamal — Homelessness is up 10 percent in Minnesota according to a study by the Wilder Foundation. Since 2016 eviction filings in court have ballooned by 42 percent. Actual evictions rose about 60 percent during that same period of time, according to the Olmsted County District Court. Last fall, the growing caseload forced the court to add a second day to its weekly calendar to hear all of them. Karen Nath is part of the legal team for Olmsted County and says this prompted them to step in and find a solution. So, they applied for a grant from the Mayo Clinic and beat out three other applicants. With the $50,000 they received they came up with an eviction clinic. The clinic takes place two times a week.

KIMT, Mayo Clinic Health System Albert Lea and Austin receive top honor by Jeremiah Wilcox — Mayo Clinic Health System's Austin and Albert Lea campuses received a major honor. They're getting a five-star rating from The Centers for Medicare & Medicaid Services. CMS updated hospital performance data on the hospital compare website on data.medicare.gov. The rating helps to empower patients, families, and stakeholders with important information they need to compare hospitals and make informed healthcare decisions. Out of the thousands of hospitals throughout the country, nearly 300 have earned top ratings. That puts a smile on Kristin Johnsons face. “It recognizes the high quality and the high standard of care our physicians providers, nurses, and all of our staff have for the care of the patients,” said Johnson.

KIMT, Mayo Clinic launces campaign for Donate Life Month by Annalisa Pardo — According to the United Network for Organ Sharing, 113,689 patients are currently on the waiting list for an organ transplant. According to Mayo Clinic, about 3,000 of their patients are on a waiting list, which is why the world-renowned clinic is asking people to help. With April being Donate Life Month, the hospital launched a campaign to get 600 people registered as donors throughout the month. Within 24 hours of the launch, over 750 people signed up. Director of the Transplant Center at Mayo Clinic, Dr. Charles B. Rosen, described himself as ‘delighted’ by the news. “I think that it’s wonderful that people have answered the call and have agreed to register as a potential donor,” he said. Additional coverage: WKBT La Crosse

Pioneer Press, Timberwolves’ Robert Covington undergoes surgery on knee to solve swelling by Jace Frederick — Covington underwent surgery in the morning at Mayo Clinic in Rochester, Minn., for debridement and to remove loose bodies in his right knee. That is expected to solve the swelling issue and send Covington back on the road toward a full recovery. That type of side effect from a bone bruise as severe as the one Covington experienced is thought to be common. Covington was already expected to miss the rest of the season. He is still out indefinitely. Additional coverage: Star Tribune, Becker’s Spine Review

Star Tribune, Minnesota briefs: Bill seeks $7 million for Rochester airport — The state’s second-busiest airport needs one of its two runways replaced, and officials there have asked the state to kick in $7 million to help pay for it. The Rochester International Airport (RST) also needs to upgrade lighting and electronics for guiding planes when visibility is poor, said executive director John Reed. Nearly 375,000 people passed through the airport in 2018. RST also handles huge volumes of patient specimens destined for the Mayo Clinic, and Mayo officials added their letters of support to Reed’s request for state funds. Some $40 million from the Federal Aviation Authority and $5 million from the city of Rochester has already been set aside for the runway work.

Star Tribune, Cremation workers could be at risk, if patients received new cancer treatment by Christopher Snowbeck — New treatments that target cancer with radioactive drugs are raising questions about whether they create a health risk for workers who cremate the bodies when the patients die. In February, doctors at the Mayo Clinic in Arizona published findings in an influential journal of low-level radiation contamination at a crematory that handled the remains of a patient who received one of the new “radiopharmaceutical” treatments. One month after the cremation, testing revealed traces of radiation in the crematory oven, vacuum filter and bone crusher. “Certainly, in our case, the dose to the crematory operator was very low. And because the dose was low, the risk is also very low,” said Kevin Nelson, a radiation physicist at Mayo Clinic in Arizona. “But if that person is continually exposed, what happens with the risk? That’s where I really think we need additional studies.” Additional coverage: Post-Bulletin

MinnPost, In a world of options, genetic testing may help identify the right psychiatric medication by Andy Steiner — Years before, the couple had a close friend who had struggled to find the right medication to treat her psychosis. She got help after physicians at the Mayo Clinic ran a genetic test that identified psychiatric medications that were a safe match for her DNA. These tests, which were developed in the last 15-20 years, are now widely available, and are known as pharmacogenomic tests.

News4Jax, The Dangers of Diet Soda with the Mayo Clinic

Orlando Sentinel, UCF QB McKenzie Milton believes he will play football again by Matt Murschel — Milton said his doctor at the Mayo Clinic in Minneapolis later explained to him that 50 percent of people who suffer similar injuries usually have to have the leg amputated because the artery has been too damaged or severed and it’s too late to get the blood flow back to the leg. Milton’s surgery started less than three hours after the injury.

Arizona Republic, There's a new blood test to screen for colon cancer. So should you skip the colonoscopy? by Stephanie Innes — Dr. Suryakanth R. Gurudu, a gastroenterologist at Mayo Clinic in Arizona who researches colon cancer prevention, said he's not familiar enough with the BeScreened-CRC to say whether it's effective, though the idea of a blood test is promising. He did note that the company's stated 94 percent accuracy rate is backed up with a study of 110 people, which is not a very large sample. "They need to have a more robust study using thousands of patients, to say if this is good for Stage One cancer detection as well," Gurudu said. "If you don't, then it's an inferior quality screening test." The test measures three protein markers that Weber says indicates the presence or absence of colorectal cancer. The company recommends it for people ages 50 through 85. The company's information for physicians does not mention precancerous lesions, said Gurudu, who reviewed the test's online marketing materials at the request of The Arizona Republic, but was otherwise unfamiliar with it. Additional coverage: USA Today

Mankato Free Press, Businesses open their doors to help eighth graders choose careers by Krisitne Goodrich — The lights and sirens are on only when there is a critical patient, lead paramedic Kathy Lamont told eighth graders as they peeked into her ambulance. “If we don't have lights and sirens, it doesn't mean we don't have a patient in back,” she told the youth visitors to the Mayo Clinic Ambulance headquarters in Mankato. While everyone else on the road is supposed to pull off to the right side of the road, sometimes those emergency alerts can distract the other drivers and cause accidents or backups. So the paramedics and EMTs use their lights and sirens judiciously.

Mankato Free Press, Mayo Clinic Health System expanding, hiring by Brian Arola — As Mayo Clinic Health System’s footprint in Mankato expands, new hires keep the growing operation humming. The health system employs 1,890 people in Mankato, part of 3,410 total in its southwest Minnesota region. The organization hires throughout the year, with current openings for emergency, family and adult sleep medicine physicians among 142 total postings. Through nationwide physician shortages, Regional HR Director Beth Dittbenner said being tied into the Mayo Clinic network serves as a strong pull factor for applicants. “That’s very attractive, I think, when you think about family medicine or emergency medicine physicians, to have those resources available and the collaboration,” she said.

Mankato Free Press, Boys & Girls Club members say ‘Bon Appetit’ by Brian Arola — Mayo Clinic Health System in Mankato piloted its “Teaching Kitchen” Tuesday at the club to teach kindergarten through eighth graders nutritious snack and meal ideas they could make at home. “The hope is that they can take away some creative ideas for healthy but also tasty snacks,” said Allie Metzler, a Mayo in Mankato physician assistant in pediatrics. “I think that so much of a kid’s day involves using their brain for focus, and really healthy foods is the foundation to helping them be able to focus.” Additional coverage: KEYC Mankato

Mankato Free Press, RUNNING TIME: Early spring weather sends runners outdoors, but experts encourage mindfulness to avoid injury by Robb Murray — Using caution and taking care to focus on a few key points can minimize the occurrence of many injuries, said Dr. Jacob Ziegler, orthopedic surgeon with Mayo Clinic Health System in Mankato. For starters: Get yourself some good running shoes, he said. To give you an idea of where to start when shopping for shoes, pay attention to the water mark your foot makes on the floor when you step out of the shower, Ziegler said. If your footprint is mostly the outline and toes without much of the middle of the foot, you probably have a high arch. If more of the middle of the foot shows, you are probably more flat-footed. Also, Ziegler said not to worry too much about having a “perfect” running gait because everyone will be different. Even experienced runners may land differently on either foot.

KEYC Mankato, Symptoms, Remedies For Restless Leg Syndrome by Sarah Meilner — Margie Bach a Nurse Practitioner with Mayo Clinic Health System joined KEYC News 12 This Morning to talk about Restless Leg Syndrome. Bach shared what some of the symptoms of RLS are and when to know when you should go to your doctor.

Fairmont Sentinel, Neist, team envision new beginnings — Things might seem a little out of focus on Monday at the eye clinic at Mayo Clinic Health System in Fairmont. It will mark the first day without a trio of long-time co-workers following the retirements of Dr. Roger Neist, ophthalmologist, and licensed practical nurses Barb Goraczkowski and Marlene Libra.

Red Wing Republican Eagle, Continuing to CARE for the uninsured — "Integrated health care for the underserved provided for the community by the community" is the vision of the Red Wing CARE Clinic. An acronym for Community, Access, Resources, and Education, the clinic is run almost entirely by volunteers and offers a variety of services free of charge. "This is really the community's clinic," said Julie Malyon, president and clinical director of the CARE Clinic…The clinic recently moved to 906 College Ave. in the Mayo Clinic Health System Seminary Professional Building. Malyon said the space that was once a nursing home is generously rented to them by Mayo Clinic Health System for only $1 a year. This new location provides even more space for the services offered which include: medical, dental, optical, pharmaceutical and physical therapy. There are also free attorney and lawyer services and educational sessions on topics like diabetes and nutrition.

WKBT La Crosse, Local doctors say FDA changes to breast cancer screening overdue by Alex Fischer — Dr. Rich Ellis, a clinical breast radiologist at Mayo Clinic Health System, said the Institute of Medicine made similar recommendations about five years ago. "Many institutions have actually already implemented them, because we recognize and want to provide the highest level of care for our patients," said Ellis. Annual screening mammagraphs are reccomended starting at 40. If you have additional risks, including dense breast tissue, talk with your doctor about options.

WKBT La Crosse, New numbers show flu season still in effect in La Crosse area — The Centers for Disease Control and Prevention is warning people the flu season is not over yet.

WKBT La Crosse, Community gathers to combat Alzheimer's — A town hall style meeting in La Crosse brought people together in the fight against Alzheimer's disease.

WKBT La Crosse, Local hospitals celebrate Doctor's Day by giving back to community by Alex Fischer — Both Gundersen Health System and Mayo Clinic Health System donated thousands of dollars to charities in our area to celebrate Doctor's Day on Saturday. Gundersen donated $3,000 to The Wafer Food Pantry in La Crosse and gave $500 each to 28 other food pantries in our area. Mayo gave more than $5,000 to 10 area charities such as The Emergency Food Basket in Onalaska and The Coulee Council on Addictions in La Crosse. Additional coverage: La Crosse Tribune

WKBT La Crosse, Mayo Clinic hospital in La Crosse receives 5 star rating from national assessment — Mayo Clinic hospital in La Crosse was given the highest quality rating possible by the Centers for Medicare & Medicaid Services. The hospital received a five-star rating. More than 3,500 hospitals were assessed nationwide and fewer than 300 were given the five-star rating. Mayo Clinic Health System leaders says the high rating wouldn't be possible without its hardworking staff.  "We owe it to our dedicated staff. They're terrific and they take great care of our patients putting the needs of the patient first," said Paul Mueller, Regional Vice President for Mayo Clinic Health System Southwest Wisconsin. Additional coverage: WXOW La Crosse

WXOW La Crosse, Focusing on women’s health by Kevin Millard — The official observance of Women’s Health Month doesn’t arrive until May. There was a preview Tuesday in La Crosse as two women shared their insight into the unique health challenges facing women. Dr. Margaret Grenisen and Dr. Stephanie Faubion spoke about advances in women’s health and why this topic is so important. Women’s health centers may be common now, but were revolutionary when introduced in the 90s. Dr. Grenisen says women have different needs from men, with more known chronic illnesses and psycho-social issues. Additional coverage: WKBT La Crosse

WEAU Eau Claire, National Donate Life Month — Join Mayo Clinic Health System in Eau Claire on Monday, April 1, to kick off National Donate Life Month by participating in Pause to Give Life — a statewide Donate Life flag-raising ceremony and moment of silence to honor donors and their families, and promote the mission of organ, tissue and eye donation. Simultaneously with dozens of other hospitals and organizations, the Donate Life flag will be raised at 10:08 a.m. near the Albert J. and Judith A. Dunlap Cancer Center entrance to highlight the fact that one donor can save eight lives. Silence will then be observed for 1 minute and 14 seconds to recognize the more than 114,000 patients waiting for a lifesaving transplant.

Next Avenue, Should All People 65+ Get Cognitive Assessments? by Edie Grossfield — Neurologist Dr. Ronald Petersen, director of the Mayo Clinic Alzheimer’s Disease Research Center in Rochester, Minn., agrees that there are significant problems with brief cognitive tests, like the Mini-Cog, but still believes regular cognitive assessments should begin at age 65. “I’m a neurologist, so I’m a specialist, and I sometimes cringe at those very, very coarse assessments of a complicated operation — namely cognitive function,” Petersen says. “But on the other hand, is something better than nothing?” He says there’s plenty of debate about which brief assessments are better than others, “and studies show that ones that are a little more detailed and take a little longer to do, in fact, give you more information about the future outcome.”

Health, Yes, It's Possible to Get Genital Psoriasis—and It Can Be Seriously Upsetting by Amanda MacMillan — For people who live with genital psoriasis, the condition is all too familiar. But for those who have no experience with the disease, the idea that the skin condition can affect the genitals may be surprising—and, yes, even a little scary. But Alina Bridges, DO, a dermatologist at the Mayo Clinic in Rochester, Minnesota, says it’s important for people to understand that psoriasis on the genitals is similar to psoriasis elsewhere on the skin: It’s not contagious, she says, and it has nothing to do with how clean or hygienic a person is…“It’s not that unusual of a location to get psoriasis, and sometimes people get it just there by itself and nowhere else,” says Dr. Bridges. “Other times, people have it around their genitals as part of generalized psoriasis all over their bodies.”

Modern Healthcare, Health system panelists discuss how to get partnerships right by Tara Bannow — …It’s not as simple as it sounds, especially for large systems with legal, reputational and financial issues to consider. At Rochester, Minn.-based Mayo Clinic, for example, executives don’t even use the word partnership, as it can be misunderstood. Instead, Mayo dubs them “alliances” and “consortiums,” said Dr. Lois Krahn, Mayo Clinic Arizona’s interim CEO.

HuffPost, These 'Harmless' Evening Habits Are Totally Messing Up Your Sleep by Beth Krietsch — You’re not alone if you’ve ever taken Benadryl or some other over-the-counter medicine to help you fall asleep. But this isn’t the greatest idea, the Mayo Clinic explains. For one, your body can quickly develop tolerance to Benadryl and other sleep aids containing antihistamines, so after taking them for a while they won’t help you sleep as easily. Meanwhile, they can also leave you feeling sluggish and tired the day after, and your sleep quality may not be that great. Additional coverage: HuffPost India

Woman’s Day, 16 Ways to Banish Back Pain Right Now by Abigail Cuffey — Stop smoking (if you do). According to the Mayo Clinic, smoking decreases blood flow to the spine, which may result in a lack of nutrients to the crucial disks that act as cushions between each back bone. Lighting up can also lead to slower healing if you already suffer from back pain. There are several ways to quit cigarettes, if you need a place to start.

Forbes, Don't Mail In That DNA Kit Until You Know These Facts by Nicole Fisher — Without cures or highly effective symptomatic treatments to go hand-in-hand with genetic testing, the risk and reward of results will certainly take a toll on individuals, families, health care markets and communities. Perhaps it is true that ignorance is bliss. But if you disagree and decide to participate in genetic or ancestry testing here is some added information and advice from the Mayo Clinic that might help you and your family through the process.

Slate, Everything You Wanted to Know About the Two-Wombed Woman Who Gave Birth Twice in 26 Days by Shannon Palus — How does this happen? When a female fetus is in utero, the uterus develops as two tubes, which eventually merge together to form the uterus, according to the Mayo Clinic. Sometimes the merging goes awry. These two uteruses are small, so they don’t take up additional space, which means people often don’t learn about them until late in the game. It’s possible that this failure to totally merge is genetic, but it’s hard to tell. Additional coverageNew York Daily News, News4Jax, Live Science

Health Leaders, Adopt new approach to coaching patients with multiple morbidities by Christopher Cheney — In an article published last month in Mayo Clinic Proceedings, capacity coaching was presented as an effective intervention for the increasing number of older patients with comorbidities…The lead author of Mayo Clinic Proceedings article told HealthLeaders that capacity coaching addresses an unmet need among older patients with multiple chronic conditions."Healthcare has not evolved to care for these patients in the ways consistent with their needs. Specifically, patients living with multiple chronic conditions are often overwhelmed by the work they must do to care for their illnesses—appointments, medication taking, dietary restrictions, and physical activity. These tasks exceed their capacity to cope with them alongside everyday life," said Kasey Boehmer, PhD, MPH, assistant professor of health services research at Rochester, Minnesota-based Mayo Clinic.

Diplomat magazine, Interview with Dr. Stephen Cassivi — Construction is under way to transform 15 Portland Place into a new premium health clinic – the first launch from a new joint venture between two of the world’s leading names in healthcare and medical research. Mayo Clinic Healthcare in partnership with Oxford University Clinic sees US hospital group Mayo Clinic and Oxford University Clinic, itself a joint venture between University of Oxford and Oxford University Hospitals NHS Foundation Trust, join forces to open a new healthcare facility in the Harley Street Medical Area, marking Mayo Clinic’s first UK venture.

Cosmos magazine, Doctors need to bone up on spaceflight risks — Writing in the New England Journal of Medicine, Jan Stepanik, Rebecca Blue and Scott Parazynski, all of the Aerospace Medicine and Vestibular Research Laboratory at the Mayo Clinic in Arizona, US, outline the potential challenges to doctors and their patients of a widely predicted shift from a state to a privately funded space industry. Until now, they say, all astronauts have been rigorously healthy and fit people who have to match the high standards imposed by NASA and other state-owned space agencies around the world. This, they note, is all about to change. “The emergence of privatised commercial spaceflight is expected to afford paying customers, including those with pre-existing health conditions, the opportunity to fly in space,” they write.

Air & Space Magazine, Exposed on the Space Station by Dirk Schulze-Makuch — BIOMEX, which stands for Biology and Mars Experiment, is led by Jean-Pierre de Vera from the German AeroSpace Center. Its purpose is to investigate the limits of life, while creating a database of which biological markers are retained when microorganisms are exposed to harsh environmental stresses—especially ultraviolet irradiation, desiccation, and low temperature…Although this meeting officially ends the BIOMEX project, research will continue, and more exciting insights may come in the future, for example from single-cell sequencing analyses of microbes exposed to space and simulated Mars conditions. That work is currently done in Marina Walther-Antonio’s lab at the Mayo Clinic, with the goal of revealing what genetic changes are caused by space conditions.

Bustle, Seasonal Affective Disorder Can Happen In The Spring & Here's What You Need To Know by Mika Doyle — It’s important to note that seasonal depression isn’t as simple as how much sunlight you’re getting, Mayo Clinic psychologist Craig Sawchuk, PhD, LP, tells Bustle. When it comes to finding relief from spring SAD or any seasonal depression, Sawchuk says, “Sunlight is still a good thing, but typically we want to emphasize additional factors, such as maintaining a normal daily routine, [such as] the sleep-wake cycle, regular nutrition, social rhythms, getting physical activity and exercise, [because] seasonal changes in mood are often associated with fatigue [and] the tendency to want to sleep, staying connected with social supports, and making plans to increase the frequency of engaging in meaningful activities across a given week. These are typically viewed as ‘natural antidepressants.’”

Bustle, 21 Things To Know About Migraines Not Everyone Realizes by Brandi Neal — While a lot of people throw around the word migraine to describe a headache, it's actually a neurological disorder that's much more than head pain. "A migraine can cause severe throbbing pain or a pulsing sensation, usually on just one side of the head. It's often accompanied by nausea, vomiting, and extreme sensitivity to light and sound," the Mayo Clinic explained on its website.

Orthopedics This Week, Award winning paper has tips for avoiding re-revision by Elizabeth Hofheinz — The study, “Why Are Contemporary Revision Total Hip Arthroplasties Failing? An Analysis of 2,500 Cases,” appears in the January 23, 2019 edition of The Journal of Arthroplasty. Co-author Matthew Abdel, M.D., professor of orthopedic surgery and consultant in the Department of Orthopedic Surgery at Mayo Clinic in Rochester, Minnesota, explained that two coincidental but tangentially related trends in hip revision surgery appear to be occurring in orthopedics. According to Dr. Abdel, “We completed this investigation given the fact that revision total hip arthroplasties (THAs) are increasing; however, revision implants and techniques have evolved and improved. As such, we were interested in the most common indications for re-revision THA in a contemporary series.”

Becker’s Hospital Review, 9 tips for young nurses seeking leadership positions by Mackenzie Bean — Many professional development strategies exist for young nurses looking to step into higher leadership positions, Tyler Faust, MSN, RN, a nurse manager at Rochester, Minn.-based Mayo Clinic, wrote in a blog post for Nurse.org. Mr. Faust listed nine tips he wished he knew earlier in his career…

WCIA Illinois, Chance connection decades ago saves a life by Jennifer Roscoe — …Huseth was dying. She needed a liver transplant and a living donor was her best hope. Wilkey told her she wanted to help and asked what she could do. She was ready to pack her bags again. "I love her and I don't want her to die. If this is what I have to do then ok. I never felt so sure about anything in my life." The two long lost friends were reunited during their final testing at the Mayo Clinic. Wilkey was a perfect match and surgery was a go.The two long lost friends were reunited during their final testing at the Mayo Clinic. Wilkey was a perfect match and surgery was a go.

MedPage Today, Skip the Turf Wars, Improve Endovascular Stroke Therapy Access? by Nicole Lou — "In rural areas and in small- to medium-sized communities without CSCs [comprehensive stroke centers] or 'stroke-ready' teams, skilled extracranial interventionists can play a critically important role in stroke intervention," according to David Holmes, Jr., MD, an interventional cardiologist at the Mayo Clinic in Rochester, Minnesota, and L. Nelson Hopkins, MD, a neurosurgeon at the University at Buffalo, New York. There are only 800 to 1,100 neurointerventionalists across the country but nearly 10,000 interventional cardiologists, radiologists, and vascular surgeons who could expand future stroke teams, Holmes and Hopkins said in their review article published in the April 2 issue of the Journal of the American College of Cardiology (JACC).

Healio, Certain symptoms indicate bloodstream infection in patients with cardiac device pocket infections — Patients with cardiovascular implantable electronic device pocket infections who meet criteria for systemic inflammatory response syndrome or are hypotensive at admission — or both — are more likely to have underlying bloodstream infections and should immediately be started on empiric antibiotics after blood cultures are obtained, researchers suggested. “Cardiovascular implantable electronic device (CIED) infections have been recognized as a growing problem, with [a] reported incidence of 1% for initial placement and up to 7% for device re-intervention,” Zerelda Esquer Garrigos, MD, from the division of infectious diseases at the Mayo Clinic College of Medicine and Science, and colleagues wrote.

Medscape, Death, Severe Impairments Still Common for Tiniest Preemies by Nicola M. Parry — Extremely preterm infants born weighing less than 400 grams (0.9 lb) are at high risk for significant morbidity and mortality, according to data published online March 25 in JAMA Pediatrics. "[Y]et with active treatment, survival to discharge and to 18 to 26 months' [corrected age (CA)] are possible," write Jane E. Brumbaugh, MD, Mayo Clinic, Rochester, Minnesota, and colleagues. "Among the 19 infants in the 2008 to 2015 birth cohort who completed follow-up evaluation (10% of liveborn infants; 21% of actively treated infants), 14 (74%) had neurodevelopmental impairment."

Medical Device Network, Breath Diagnostics and Mayo Clinic partner on new lung cancer test — Breath Diagnostics has partnered with Mayo Clinic Laboratories to create clinical diagnostic tests that analyse breath samples. The collaboration aims to identify individual predictive biomarkers for a variety of diseases, including lung cancer. The partners intend to develop a non-invasive, quick and cost-effective test to identify indeterminate pulmonary nodules and monitor for potential recurrence of cancer following surgery.

MD Magazine, Association of PET with Changes in Management of Patients with Dementia, MCI by Patrick Campbell — Clifford Jack Jr, MD, professor of radiology at the Mayo Clinic, and Ronald Petersen, MD, PhD, professor of neurology at the Mayo Clinic, wrote an editorial regarding the IDEAS study. While the writers were optimistic of the findings, they pointed that several factors should be considered when analyzing findings of the study. “Although the findings of the IDEAS study show that improved knowledge about etiology provided by amyloid PET, over and above current standards of clinical care, changes clinical management, there are important nuances to this broad conclusion,” Jack and Petersen wrote.

Neurology Today, In the Pipeline-Alzheimer's Disease by Jamie Talan — Commenting on the study, Ronald C. Petersen, MD, PhD, FAAN, the Cora Kanow Professor of Alzheimer's Disease Research at Mayo Clinic College of Medicine in Rochester, MN, said: “This is a nicely designed study to answer whether amyloid imaging and other biomarkers can predict the progression of MCI to AD down the road. It is confirmation of what we have been thinking about for some time. If a person with MCI has a positive PET scan and positive MRI scan (of the hippocampus volume) we can say that they will progress more rapidly than those who have negative tests.”

Alzforum, Results from IDEAS Study Published — IDEAS was born of the Centers for Medicare & Medicaid Services’ (CMS) desire to know if reimbursing for these expensive scans would be worthwhile. Sixteen thousand and eight , volunteers with mild cognitive impairment or mild dementia took part. They had no clear diagnosis when enrolled but Alzheimer’s disease had to have been a possibility. They were seen by 946 dementia specialists at 595 U.S. sites. Of the 11,409 who completed the study, 6,971 had a positive PET scan. Diagnosis for 2,860 patients changed from AD to non-AD, and for 1,201 patients from non-AD to AD. Between pre- and 90 days post scan, physicians changed treatment for 7,018 patients. They changed AD drug therapy, other drug therapy, or initiated counseling about safety and life planning. “This supports (but without randomization does not prove) a relationship between the PET findings and post-PET changes in management,” wrote Clifford Jack and Ronald Petersen, Mayo Clinic, Rochester, Minnesota, in a JAMA editorial.

Alzforum, FDA Panel Rejects Neuronix Brain Stimulation Device — An advisory panel appointed by the FDA was nearly unanimous in recommending yesterday that Yokneam, Israel-based Neuronix not be allowed to market its neuroAD Therapy System in the U.S. Approved for AD in Europe, Australia, and Israel, the device combines repetitive transcranial magnetic stimulation (rTMS) and cognitive training in what it claims to be a memory-improving therapy for people in the early stages of Alzheimer’s disease. However, the company’s Phase 3 data of a six-week treatment trial missed its primary endpoint. As outlined in a brief FDA summary, “The Panel was in unanimous agreement that the probable benefits to health of the neuroAD Therapy System do not outweigh the probable risks to health.” “There may be some value for TMS in cognitive therapy, but the current pivotal trial certainly didn’t demonstrate it,” said David Knopman, Mayo Clinic, Rochester Minnesota, a voting member of the panel. “The sponsor needs to do a properly designed, larger, longer trial.”

Al Roeya, Alzheimer’s and paralysis by Mohamed Mansour — Mayo Clinic experts succeeded in converting stem cells into large groups of brain neurons, grouped into a test tube and resembling a small brain, which could be used in experiments aimed at treating various brain diseases. The brains, stored in test tubes, may seem like scenes from a terrifying fantasy film, but scientists use them to understand deadly diseases such as Alzheimer's and Parkinson's.

La Nacion Opioides: capacitan en el uso de las drogas que tienen en vilo a EE.UU. — The excess of medical prescription encouraged by excessive and biased advertising from the pharmaceutical industry with messages such as opioids are not addictive when used to treat pain in addition to overexposure to these drugs, their use for unauthorized indications and poor training of professionals contributed, along with misinformation of the population, to the onset of the overdose epidemic, explained Halena Gazelka, pain medicine specialist and director of the program of Rational Use of Opioids at Mayo Clinic in Rochester, Minnesota.

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