September 26, 2019

‘Silent’ celiac disease common in patients’ close relatives

By Karl Oestreich

by Tamara Mathias

When a family member has celiac disease, Mayo Clinic researchers recommend parents, siblings and children also be tested, after a new study suggests first-degree relatives frequently have the condition, too - often without typical symptoms…The study, published in Mayo Clinic Proceedings, found that 44% of close relatives who had blood tests for celiac disease turned out to have the condition. Nearly all of them had atypical symptoms or no symptoms at all.

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Context: Parents, siblings and children of people with celiac disease are at high risk of also having the disease, according to a Mayo Clinic study. This study calls for screening of all first-degree relatives of patients — not just those who show symptoms.

The retrospective study, to be published in Mayo Clinic Proceedings in September, found that 44% of screened first-degree relatives had celiac disease. Of those patients, 94% had symptoms that were not classic or had no symptoms at all.

"Research has shown that family members of celiac disease patients are at higher risk, and we used our Mayo Clinic data to show that proactive screening of first-degree relatives, regardless of whether they showed symptoms, resulted in diagnoses that would have been missed," says Imad Absah, M.D., a Mayo Clinic pediatric gastroenterologist and the study's lead author. You can read more about the study on Mayo Clinic News Network.

Contact: Joe Dangor

Tags: celiac disease, Dr. Imad Absah, Mayo Clinic Proceedings, Reuters, Uncategorized

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