Hematology
October 22, 2009
High-dose dexamethasone is a mainstay of therapy for multiple myeloma. We studied whether low-dose dexamethasone in combination with lenalidomide is non-inferior to and has lower toxicity than high-dose dexamethasone plus lenalidomide… Lenalidomide plus low-dose dexamethasone is associated with better short-term overall survival and with lower toxicity than lenalidomide plus high-dose dexamethasone in patients with […]
Tags: dexamethasone, oncology
October 21, 2009
Resident Fatigue, Distress Can Lead to Medical Errors, Says Study
A Mayo Clinic study published recently in the Journal of the American Medical Association, or JAMA, says that residents who experienced high levels of either fatigue or distress — or both — were more likely to report a medical error. The study reinforces the importance of managing residents’ sleep needs and maintaining their feelings of […]
Tags: medical errors, resident fatigue
October 5, 2009
Turning Point: During transplant recovery, she had time to recall how lucky she is
In the fall of 2006, Michele Vance, 61, of New Brighton went in for her annual physical. Her doctor decided she should get her blood work done because she hadn’t had the tests for a while… “That September, I was diagnosed with myelodysplastic syndrome with emerging leukemia. It is an early onset to leukemia. […]
Tags: leukemia
September 10, 2009
Cytopia’s CYT387 Receives FDA Clearance to Start US Clinical Trials
Cytopia Limited’s (ASX: CYT) Investigational New Drug Application (IND) for CYT387 has passed US Food and Drug Administration (FDA) review. CYT387 is a small-molecule oral JAK1/JAK2 kinase inhibitor designed to treat various hematological disorders… Preparations for the company’s initial Phase I/II trial of CYT387 in patients with myelofibrosis are currently being finalized. Myelofibrosis is […]
Tags: clinical trials, Hematology
August 26, 2009
Mayo Clinic Proceedings: Common blood disorder may not be linked to as many serious diseases
A symptomless blood disorder, monoclonal gammopathy of undetermined significance, known as MGUS, is not linked to as many serious diseases as previously thought. This finding may save patients from undergoing unnecessary workup and treatment according to a study published in the August 2009 issue of Mayo Clinic Proceedings. First Science, 8/25/09 Additional coverage: […]